Novel Antibody Capture Assay for Paraffin‐Embedded Tissue Detects Wide‐Ranging Amyloid Beta and Paired Helical Filament–Tau Accumulation in Cognitively Normal Older Adults

Quantifying antigens in formalin‐fixed tissue is challenging and limits investigation in population‐based studies of brain aging. To address this major limitation, we have developed a new technique that we call “Histelide”: immunohistochemistry (HIST‐) and enzyme‐linked immunosorbent assay (ELISA) (...

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Autores principales: Postupna, Nadia, Rose, Shannon E., Bird, Thomas D., Gonzalez‐Cuyar, Luis F., Sonnen, Joshua A., Larson, Eric B., Keene, C. Dirk, Montine, Thomas J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Publishing Ltd 2011
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Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3295908/
https://ncbi.nlm.nih.gov/pubmed/21999410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2011.00542.x
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