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Butyrate Attenuates Lipopolysaccharide-Induced Inflammation in Intestinal Cells and Crohn's Mucosa through Modulation of Antioxidant Defense Machinery

Oxidative stress plays an important role in the pathogenesis of inflammatory bowel disease (IBD), including Crohn's disease (CrD). High levels of Reactive Oxygen Species (ROS) induce the activation of the redox-sensitive nuclear transcription factor kappa-B (NF-κB), which in turn triggers the i...

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Hlavní autoři: Russo, Ilaria, Luciani, Alessandro, De Cicco, Paola, Troncone, Edoardo, Ciacci, Carolina
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3295784/
https://ncbi.nlm.nih.gov/pubmed/22412931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032841
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