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Butyrate Attenuates Lipopolysaccharide-Induced Inflammation in Intestinal Cells and Crohn's Mucosa through Modulation of Antioxidant Defense Machinery

Oxidative stress plays an important role in the pathogenesis of inflammatory bowel disease (IBD), including Crohn's disease (CrD). High levels of Reactive Oxygen Species (ROS) induce the activation of the redox-sensitive nuclear transcription factor kappa-B (NF-κB), which in turn triggers the i...

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Detalhes bibliográficos
Main Authors: Russo, Ilaria, Luciani, Alessandro, De Cicco, Paola, Troncone, Edoardo, Ciacci, Carolina
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3295784/
https://ncbi.nlm.nih.gov/pubmed/22412931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032841
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