Histone deacetylase inhibitor, butyrate, attenuates lipopolysaccharide-induced acute lung injury in mice

BACKGROUND: Histone deacetylase (HDAC) inhibitors, developed as promising anti-tumor drugs, exhibit their anti-inflammatory properties due to their effects on reduction of inflammatory cytokines. OBJECTIVE: To investigate the protective effect of butyrate, a HDAC inhibitor, on lipopolysaccharide (LP...

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Main Authors: Ni, Yun-Feng, Wang, Jian, Yan, Xiao-Long, Tian, Feng, Zhao, Jin-Bo, Wang, Yun-Jie, Jiang, Tao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848144/
https://ncbi.nlm.nih.gov/pubmed/20302656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-11-33
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