TAK-1/p38/nNFκB signaling inhibits myoblast differentiation by increasing levels of Activin A

BACKGROUND: Skeletal-muscle differentiation is required for the regeneration of myofibers after injury. The differentiation capacity of satellite cells is impaired in settings of old age, which is at least one factor in the onset of sarcopenia, the age-related loss of skeletal-muscle mass and major...

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Autores principales: Trendelenburg, Anne Ulrike, Meyer, Angelika, Jacobi, Carsten, Feige, Jerome N, Glass, David J
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3295657/
https://ncbi.nlm.nih.gov/pubmed/22313861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2044-5040-2-3
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