Biochemical selectivity of oral versus intravenous aspirin in rats. Inhibition by oral aspirin of cyclooxygenase activity in platelets and presystemic but not systemic vessels.

In rats intravenous aspirin was only slightly more effective an inhibitor of platelet thromboxane B2 (TxB2) than of aorta 6-keto-prostaglandin (PGF)1 alpha generation (1.9 versus 2.1 mg/kg). In contrast, oral aspirin was about five times more effective on platelet than on aorta cyclooxygenase activi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Cerletti, C, Gambino, M C, Garattini, S, de Gaetano, G
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1986
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC329565/
https://ncbi.nlm.nih.gov/pubmed/3088044
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