SUBOPTIMAL INHIBITION OF PLATELET CYCLOOXYGENASE-1 BY ASPIRIN IN METABOLIC SYNDROME

Interindividual variation in the ability of aspirin to inhibit platelet cyclooxygenase-1 (COX-1) could account for some on-treatment cardiovascular events. Here, we sought to determine whether there are clinical phenotypes that are associated with a suboptimal pharmacological effect of aspirin. In a...

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Autori principali: Smith, James P., Haddad, Elias V., Taylor, Mary B., Oram, Denise, Blakemore, Dana, Chen, Qingxia, Boutaud, Olivier, Oates, John A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418792/
https://ncbi.nlm.nih.gov/pubmed/22311905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.111.181404
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