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Suboptimal inhibition of platelet cyclo-oxygenase-1 (COX-1) by aspirin in lupus erythematosus: Association with metabolic syndrome

OBJECTIVES: Low-dose aspirin prevents platelet aggregation by suppressing thromboxane A(2) synthesis. However, in some individuals thromboxane A(2) suppression by aspirin is impaired, indicating suboptimal inhibition of platelet COX-1 by aspirin. Because patients with systemic lupus erythematosus (S...

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書誌詳細
主要な著者: Kawai, Vivian K., Avalos, Ingrid, Oeser, Annette, Oates, John A., Milne, Ginger L., Solus, Joseph F., Chung, Cecilia P., Stein, C. Michael
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946810/
https://ncbi.nlm.nih.gov/pubmed/24022862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acr.22169
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