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Saturated fatty acids induce c-Src clustering within membrane subdomains leading to JNK activation

Saturated fatty acids (FA) exert adverse health effects and are more likely to cause insulin resistance and type 2 diabetes than unsaturated FA, some of which exert protective and beneficial effects. Saturated FA, but not unsaturated FA, activate Jun N terminal kinase (JNK), which has been linked to...

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Detalhes bibliográficos
Main Authors: Holzer, Ryan G., Park, Eek-Joong, Li, Ning, Tran, Helen, Chen, Monica, Choi, Crystal, Solinas, Giovanni, Karin, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3295636/
https://ncbi.nlm.nih.gov/pubmed/21962514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.08.034
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