Spontaneous expression of the c-sis gene and release of a platelet-derived growth factorlike molecule by human alveolar macrophages.

Alveolar macrophages from normal individuals and patients with interstitial lung diseases spontaneously expressed a 4.2-kilobase mRNA complementary to the c-sis gene, a proto-oncogene coding for one of the chains of platelet-derived growth factor (PDGF). Concomitantly, these cells released a mediato...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Mornex, J F, Martinet, Y, Yamauchi, K, Bitterman, P B, Grotendorst, G R, Chytil-Weir, A, Martin, G R, Crystal, R G
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1986
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329531/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3722386/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112574
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