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Spontaneous expression of the c-sis gene and release of a platelet-derived growth factorlike molecule by human alveolar macrophages.

Alveolar macrophages from normal individuals and patients with interstitial lung diseases spontaneously expressed a 4.2-kilobase mRNA complementary to the c-sis gene, a proto-oncogene coding for one of the chains of platelet-derived growth factor (PDGF). Concomitantly, these cells released a mediato...

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Autors principals: Mornex, J F, Martinet, Y, Yamauchi, K, Bitterman, P B, Grotendorst, G R, Chytil-Weir, A, Martin, G R, Crystal, R G
Format: Artigo
Idioma:Inglês
Publicat: 1986
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC329531/
https://ncbi.nlm.nih.gov/pubmed/3722386
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