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Nucleotide excision repair (NER) machinery recruitment by the transcription-repair coupling factor involves unmasking of a conserved intramolecular interface

Transcription-coupled DNA repair targets DNA lesions that block progression of elongating RNA polymerases. In bacteria, the transcription-repair coupling factor (TRCF; also known as Mfd) SF2 ATPase recognizes RNA polymerase stalled at a site of DNA damage, removes the enzyme from the DNA, and recrui...

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Bibliografiske detaljer
Main Authors: Deaconescu, Alexandra M., Sevostyanova, Anastasia, Artsimovitch, Irina, Grigorieff, Nikolaus
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3295266/
https://ncbi.nlm.nih.gov/pubmed/22331906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1115105109
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