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Predictive microfluidic control of regulatory ligand trajectories in individual pluripotent cells

Local (cell-level) signaling environments, regulated by autocrine and paracrine signaling, and modulated by cell organization, are hypothesized to be fundamental stem cell fate control mechanisms used during development. It has, however, been challenging to demonstrate the impact of cell-level organ...

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Autors principals: Moledina, Faisal, Clarke, Geoff, Oskooei, Ali, Onishi, Kento, Günther, Axel, Zandstra, Peter W.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3295256/
https://ncbi.nlm.nih.gov/pubmed/22334649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1111478109
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