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Predictive microfluidic control of regulatory ligand trajectories in individual pluripotent cells

Local (cell-level) signaling environments, regulated by autocrine and paracrine signaling, and modulated by cell organization, are hypothesized to be fundamental stem cell fate control mechanisms used during development. It has, however, been challenging to demonstrate the impact of cell-level organ...

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Detalhes bibliográficos
Main Authors: Moledina, Faisal, Clarke, Geoff, Oskooei, Ali, Onishi, Kento, Günther, Axel, Zandstra, Peter W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3295256/
https://ncbi.nlm.nih.gov/pubmed/22334649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1111478109
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