Proteins Associated with the Exon Junction Complex Also Control the Alternative Splicing of Apoptotic Regulators

Several apoptotic regulators, including Bcl-x, are alternatively spliced to produce isoforms with opposite functions. We have used an RNA interference strategy to map the regulatory landscape controlling the expression of the Bcl-x splice variants in human cells. Depleting proteins known as core (Y1...

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Autors principals: Michelle, Laetitia, Cloutier, Alexandre, Toutant, Johanne, Shkreta, Lulzim, Thibault, Philippe, Durand, Mathieu, Garneau, Daniel, Gendron, Daniel, Lapointe, Elvy, Couture, Sonia, Le Hir, Hervé, Klinck, Roscoe, Elela, Sherif Abou, Prinos, Panagiotis, Chabot, Benoit
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3295189/
https://ncbi.nlm.nih.gov/pubmed/22203037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06130-11
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