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Proteins Associated with the Exon Junction Complex Also Control the Alternative Splicing of Apoptotic Regulators
Several apoptotic regulators, including Bcl-x, are alternatively spliced to produce isoforms with opposite functions. We have used an RNA interference strategy to map the regulatory landscape controlling the expression of the Bcl-x splice variants in human cells. Depleting proteins known as core (Y1...
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| Autori principali: | , , , , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3295189/ https://ncbi.nlm.nih.gov/pubmed/22203037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06130-11 |
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