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Protein Kinase C-Dependent Control of Bcl-x Alternative Splicing

The alternative splicing of Bcl-x generates the proapoptotic Bcl-x(S) protein and the antiapoptotic isoform Bcl-x(L). Bcl-x splicing is coupled to signal transduction, since ceramide, hormones, and growth factors alter the ratio of the Bcl-x isoforms in different cell lines. Here we report that the...

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Detalles Bibliográficos
Main Authors: Revil, Timothée, Toutant, Johanne, Shkreta, Lulzim, Garneau, Daniel, Cloutier, Philippe, Chabot, Benoit
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169420/
https://ncbi.nlm.nih.gov/pubmed/17923691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00565-07
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