Pharmacodynamics of TD-1792, a Novel Glycopeptide-Cephalosporin Heterodimer Antibiotic Used against Gram-Positive Bacteria, in a Neutropenic Murine Thigh Model

TD-1792 is a novel glycopeptide-cephalosporin heterodimer investigational antibiotic that displays potent bactericidal effects against clinically relevant Gram-positive organisms in vitro. The present studies evaluated the in vivo pharmacokinetics (PK) and pharmacodynamics (PD) of TD-1792 in the neu...

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Autors principals: Hegde, Sharath S., Okusanya, Olanrewaju O., Skinner, Robert, Shaw, Jeng-Pyng, Obedencio, Glenmar, Ambrose, Paul G., Blais, Johanne, Bhavnani, Sujata M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294954/
https://ncbi.nlm.nih.gov/pubmed/22155835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05382-11
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