Identification of Novel N-(Morpholine-4-Carbonyloxy) Amidine Compounds as Potent Inhibitors against Hepatitis C Virus Replication

To identify novel compounds that possess antiviral activity against hepatitis C virus (HCV), we screened a library of small molecules with various amounts of structural diversity using an HCV replicon-expressing cell line and performed additional validations using the HCV-JFH1 infectious-virus cell...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Kusano-Kitazume, Akiko, Sakamoto, Naoya, Okuno, Yukiko, Sekine-Osajima, Yuko, Nakagawa, Mina, Kakinuma, Sei, Kiyohashi, Kei, Nitta, Sayuri, Murakawa, Miyako, Azuma, Seishin, Nishimura-Sakurai, Yuki, Hagiwara, Masatoshi, Watanabe, Mamoru
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2012
Schlagworte:
Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294916/
https://ncbi.nlm.nih.gov/pubmed/22203602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05764-11
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge