Analysis of Interferon Signaling by Infectious Hepatitis C Virus Clones with Substitutions of Core Amino Acids 70 and 91

Substitution of amino acids 70 and 91 in the hepatitis C virus (HCV) core region is a significant predictor of poor responses to peginterferon-plus-ribavirin therapy, while their molecular mechanisms remain unclear. Here we investigated these differences in the response to alpha interferon (IFN) by...

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Hlavní autoři: Funaoka, Yusuke, Sakamoto, Naoya, Suda, Goki, Itsui, Yasuhiro, Nakagawa, Mina, Kakinuma, Sei, Watanabe, Takako, Mishima, Kako, Ueyama, Mayumi, Onozuka, Izumi, Nitta, Sayuri, Kitazume, Akiko, Kiyohashi, Kei, Murakawa, Miyako, Azuma, Seishin, Tsuchiya, Kiichiro, Watanabe, Mamoru
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2011
Témata:
Cellular Response to Infection
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126319/
https://ncbi.nlm.nih.gov/pubmed/21490101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02583-10
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