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An Epigenetic Switch Mediates Bistable Expression of the Type 1 Pilus Genes in Streptococcus pneumoniae

Expression of the pneumococcal type 1 pilus is bistable and positively regulated by the transcription factor RlrA. RlrA is also known to positively control its own expression. Here we present evidence that bistable expression of the type 1 pilus is mediated by the positive-feedback loop controlling...

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Autores principales: Basset, Alan, Turner, Keith H., Boush, Elizabeth, Sayeed, Sabina, Dove, Simon L., Malley, Richard
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294793/
https://ncbi.nlm.nih.gov/pubmed/22194460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.06078-11
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