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Emerging Role of Ubiquitination in Antiviral RIG-I Signaling

Summary: Detection of viruses by the innate immune system involves the action of specialized pattern recognition receptors. Intracellular RIG-I receptors sense the presence of viral nucleic acids in infected cells and trigger signaling pathways that lead to the production of proinflammatory and anti...

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Detalles Bibliográficos
Main Authors: Maelfait, Jonathan, Beyaert, Rudi
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294425/
https://ncbi.nlm.nih.gov/pubmed/22390971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MMBR.05012-11
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