Hepatitis B virus regulatory HBx protein binding to DDB1 is required but is not sufficient for maximal HBV replication

Robust hepatitis B virus (HBV) replication is stimulated by the regulatory HBx protein. HBx binds the cellular protein DDB1; however, the importance of this interaction for HBV replication remains unknown. We tested whether HBx binding to DDB1 was required for HBV replication using a plasmid based r...

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Hauptverfasser: Hodgson, Amanda J., Hyser, Joseph M., Keasler, Victor V., Cang, Yong, Slagle, Betty L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294142/
https://ncbi.nlm.nih.gov/pubmed/22342275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2012.01.021
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