Hepatitis B Virus Regulatory HBx Protein Binds to Adaptor Protein IPS-1 and Inhibits the Activation of Beta Interferon

Hepatitis B virus (HBV) encodes the regulatory HBx protein, which is required for virus replication, although its specific role(s) in the replication cycle remains under investigation. An immunoprecipitation/mass spectrometry approach was used to identify four novel HBx binding proteins from the cyt...

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Bibliographic Details
Main Authors: Kumar, Manish, Jung, Sung Yun, Hodgson, Amanda J., Madden, Charles R., Qin, Jun, Slagle, Betty L.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2011
Subjects:
Cellular Response to Infection
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020017/
https://ncbi.nlm.nih.gov/pubmed/21068253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01825-10
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