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Hepatitis B virus HBx protein localized to the nucleus restores HBx-deficient virus replication in HepG2 cells and in vivo in hydrodynamically-injected mice

Identifying the requirements for the regulatory HBx protein in hepatitis B virus (HBV) replication is an important goal. A plasmid-based HBV replication assay was used to evaluate whether HBx subcellular localization influences its ability to promote virus replication, as measured by real time PCR q...

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Bibliografische gegevens
Hoofdauteurs: Keasler, Victor V., Hodgson, Amanda J., Madden, Charles R., Slagle, Betty L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749295/
https://ncbi.nlm.nih.gov/pubmed/19464721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.05.001
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