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Intraspinal transplantation of GABAergic neural progenitors attenuates neuropathic pain in rats: a pharmacologic and neurophysiological evaluation

Dysfunctional γ-aminobutyric acid (GABA)-ergic inhibitory neurotransmission is hypothesized to underlie chronic neuropathic pain. Intraspinal transplantation of GABAergic neural progenitor cells (NPCs) may reduce neuropathic pain by restoring dorsal horn inhibition. Rat NPCs pre-differentiated to a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jergova, Stanislava, Hentall, Ian D., Gajavelli, Shyam, Varghese, Mathew S., Sagen, Jacqueline
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294082/
https://ncbi.nlm.nih.gov/pubmed/22193109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2011.12.005
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