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Intraspinal transplantation of GABAergic neural progenitors attenuates neuropathic pain in rats: a pharmacologic and neurophysiological evaluation

Dysfunctional γ-aminobutyric acid (GABA)-ergic inhibitory neurotransmission is hypothesized to underlie chronic neuropathic pain. Intraspinal transplantation of GABAergic neural progenitor cells (NPCs) may reduce neuropathic pain by restoring dorsal horn inhibition. Rat NPCs pre-differentiated to a...

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Detalhes bibliográficos
Main Authors: Jergova, Stanislava, Hentall, Ian D., Gajavelli, Shyam, Varghese, Mathew S., Sagen, Jacqueline
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294082/
https://ncbi.nlm.nih.gov/pubmed/22193109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2011.12.005
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