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Experimental Gene Therapy with Serine-Histogranin and Endomorphin 1 for the Treatment of Chronic Neuropathic Pain

The insufficient pain relief provided by current pharmacotherapy for chronic neuropathic pain is a serious medical problem. The enhanced glutamate signaling via NMDA receptors appears to be one of the key events in the development of chronic pain. Although effective, clinical use of systemic NMDA an...

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Pubblicato in:Front Mol Neurosci
Autori principali: Jergova, Stanislava, Gordon, Catherine E., Gajavelli, Shyam, Sagen, Jacqueline
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727090/
https://ncbi.nlm.nih.gov/pubmed/29276474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00406
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