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Epithelial cells utilize cortical actin/myosin to activate latent TGF-β through integrin α(v)β(6)-dependent physical force

Transforming Growth Factor Beta (TGF-β) is involved in regulating many biological processes and disease states. Cells secrete the cytokine as a latent complex that must be activated for it to exert its biological functions. We previously discovered that the epithelial-restricted integrin α(v)β(6) ac...

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Detalhes bibliográficos
Main Authors: Giacomini, Marilyn M., Travis, Mark A., Kudo, Makoto, Sheppard, Dean
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294033/
https://ncbi.nlm.nih.gov/pubmed/22309779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2012.01.020
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