IDH2 mutations are frequent in angioimmunoblastic T-cell lymphoma

Mutations in isocitrate dehydrogenase 1 (IDH1) and isocitrate dehydrogenase 2 (IDH2) occur in most grade 2 and 3 gliomas, secondary glioblastomas, and a subset of acute myelogenous leukemias but have not been detected in other tumor types. The mutations occur at specific arginine residues and result...

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Dettagli Bibliografici
Autori principali: Cairns, Rob A., Iqbal, Javeed, Lemonnier, François, Kucuk, Can, de Leval, Laurence, Jais, Jean-Philippe, Parrens, Marie, Martin, Antoine, Xerri, Luc, Brousset, Pierre, Chan, Li Chong, Chan, Wing-Chung, Gaulard, Philippe, Mak, Tak W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2012
Soggetti:
Lymphoid Neoplasia
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293643/
https://ncbi.nlm.nih.gov/pubmed/22215888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-11-391748
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