Hepatitis C Virus NS3/NS4A DNA Vaccine Induces Multiepitope T Cell Responses in Rhesus Macaques Mimicking Human Immune Responses

Numerous studies have suggested that an effective hepatitis C virus (HCV) vaccine must induce a strong T helper 1 (Th1) T cell response. While several therapeutic vaccine candidates have shown promise in clinical trials, response rates have been low suggesting that further optimization is important....

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Autors principals: Lang Kuhs, Krystle A, Ginsberg, Arielle A, Yan, Jian, Wiseman, Roger W, Khan, Amir S, Sardesai, Niranjan Y, O'Connor, David H, Weiner, David B
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293616/
https://ncbi.nlm.nih.gov/pubmed/21952169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.188
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