Induction of Intrahepatic HCV NS4B, NS5A and NS5B-Specific Cellular Immune Responses following Peripheral Immunization

Numerous studies have suggested that an effective Hepatitis C Virus (HCV) vaccine must induce strong cytotoxic and IFN-γ+ T cell responses targeting the non-structural region of the virus. Most importantly, these responses must be able to migrate into and remain functional within the liver, an organ...

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Detalhes bibliográficos
Main Authors: Lang Kuhs, Krystle A., Toporovski, Roberta, Ginsberg, Arielle A., Shedlock, Devon J., Weiner, David B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528776/
https://ncbi.nlm.nih.gov/pubmed/23284919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052165
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