Role of ω-hydroxylase in adenosine-mediated aortic response through MAP kinase using A(2A)-receptor knockout mice

Previously, we have shown that A(2A) adenosine receptor (A(2A)AR) knockout mice (KO) have increased contraction to adenosine. The signaling mechanism(s) for A(2A)AR is still not fully understood. In this study, we hypothesize that, in the absence of A(2A)AR, ω-hydroxylase (Cyp4a) induces vasoconstri...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ponnoth, Dovenia S., Nayeem, Mohammed A., Kunduri, Swati S., Tilley, Stephen L., Zeldin, Darryl C., Ledent, Catherine, Mustafa, S. Jamal
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Physiological Society 2012
Gaiak:
Cardiovascular and Renal Integration
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293507/
https://ncbi.nlm.nih.gov/pubmed/22160543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00481.2011
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