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Absence of adenosine-mediated aortic relaxation in A(2A) adenosine receptor knockout mice

Adenosine mediates vascular responses through four receptor subtypes: A(1), A(2A), A(2B), and A(3). The role of A(2A) receptors in aortic vascular tone was investigated using A(2A) adenosine receptor (AR) knockout (A(2A)KO) and corresponding wild-type (A(2A)WT) mice. Isolated aortic rings from A(2A)...

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Main Authors: Ponnoth, Dovenia S., Sanjani, Maryam Sharifi, Ledent, Catherine, Roush, Kevin, Krahn, Thomas, Mustafa, S. Jamal
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781374/
https://ncbi.nlm.nih.gov/pubmed/19749167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00192.2009
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