Aging reverses the role of the transient receptor potential vanilloid-1 channel in systemic inflammation from anti-inflammatory to proinflammatory

Studies in young rodents have shown that the transient receptor potential vanilloid-1 (TRPV1) channel plays a suppressive role in the systemic inflammatory response syndrome (SIRS) by inhibiting production of tumor necrosis factor (TNF)α and possibly by other mechanisms. We asked whether the anti-in...

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Detalhes bibliográficos
Main Authors: Wanner, Samuel P, Garami, Andras, Pakai, Eszter, Oliveira, Daniela L, Gavva, Narender R, Coimbra, Cândido C, Romanovsky, Andrej A
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293383/
https://ncbi.nlm.nih.gov/pubmed/22214765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.11.2.18772
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