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The Transient Receptor Potential Vanilloid-1 Channel in Thermoregulation: A Thermosensor It Is Not

The development of antagonists of the transient receptor potential vanilloid-1 (TRPV1) channel as pain therapeutics has revealed that these compounds cause hyperthermia in humans. This undesirable on-target side effect has triggered a surge of interest in the role of TRPV1 in thermoregulation and re...

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Detalhes bibliográficos
Main Authors: Romanovsky, Andrej A., Almeida, Maria C., Garami, Andras, Steiner, Alexandre A., Norman, Mark H., Morrison, Shaun F., Nakamura, Kazuhiro, Burmeister, Jeffrey J., Nucci, Tatiane B.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763780/
https://ncbi.nlm.nih.gov/pubmed/19749171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/pr.109.001263
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