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Understanding the first steps in embryonic stem cell exit from the pluripotent state

We are interested in understanding how a given cell type, in response to external cues from its environment, makes the decision to differentiate. In the case of mouse embryonic stem cells (mESC), the key external factor that maintains their undifferentiated state is the cytokine leukemia inhibitory...

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Autors principals: Luckey, C. John, Lu, Yu, Marto, Jarrod A.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293186/
https://ncbi.nlm.nih.gov/pubmed/22074622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1537-2995.2011.03374.x
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