Hmga2 is necessary for Otx2-dependent exit of embryonic stem cells from the pluripotent ground state

BACKGROUND: A crucial event in the differentiation of mouse embryonic stem cells (ESCs) is the exit from the pluripotent ground state that leads to the acquisition of the ‘primed’ pluripotent phenotype, characteristic of the epiblast-like stem cells (EpiLCs). The transcription factors Oct4 and Otx2...

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Bibliografische gegevens
Gepubliceerd in:BMC Biol
Hoofdauteurs: Navarra, Angelica, Musto, Anna, Gargiulo, Anna, Petrosino, Giuseppe, Pierantoni, Giovanna Maria, Fusco, Alfredo, Russo, Tommaso, Parisi, Silvia
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2016
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818510/
https://ncbi.nlm.nih.gov/pubmed/27036552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-016-0246-5
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