Hmga2 is necessary for Otx2-dependent exit of embryonic stem cells from the pluripotent ground state

BACKGROUND: A crucial event in the differentiation of mouse embryonic stem cells (ESCs) is the exit from the pluripotent ground state that leads to the acquisition of the ‘primed’ pluripotent phenotype, characteristic of the epiblast-like stem cells (EpiLCs). The transcription factors Oct4 and Otx2...

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Bibliografiset tiedot
Julkaisussa:BMC Biol
Päätekijät: Navarra, Angelica, Musto, Anna, Gargiulo, Anna, Petrosino, Giuseppe, Pierantoni, Giovanna Maria, Fusco, Alfredo, Russo, Tommaso, Parisi, Silvia
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2016
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818510/
https://ncbi.nlm.nih.gov/pubmed/27036552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-016-0246-5
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