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Understanding the first steps in embryonic stem cell exit from the pluripotent state

We are interested in understanding how a given cell type, in response to external cues from its environment, makes the decision to differentiate. In the case of mouse embryonic stem cells (mESC), the key external factor that maintains their undifferentiated state is the cytokine leukemia inhibitory...

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Detalhes bibliográficos
Main Authors: Luckey, C. John, Lu, Yu, Marto, Jarrod A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293186/
https://ncbi.nlm.nih.gov/pubmed/22074622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1537-2995.2011.03374.x
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