TLR3 signaling is either protective or pathogenic for the development of Theiler's virus-induced demyelinating disease depending on the time of viral infection

BACKGROUND: We have previously shown that toll-like receptor 3 (TLR3)-mediated signaling plays an important role in the induction of innate cytokine responses to Theiler's murine encephalomyelitis virus (TMEV) infection. In addition, cytokine levels produced after TMEV infection are significant...

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Detalhes bibliográficos
Main Authors: Jin, Young-Hee, Kaneyama, Tomoki, Kang, Min Hyung, Kang, Hyun Seok, Koh, Chang-Sung, Kim, Byung S
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293102/
https://ncbi.nlm.nih.gov/pubmed/22189096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-178
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