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TLR3 signaling is either protective or pathogenic for the development of Theiler's virus-induced demyelinating disease depending on the time of viral infection

BACKGROUND: We have previously shown that toll-like receptor 3 (TLR3)-mediated signaling plays an important role in the induction of innate cytokine responses to Theiler's murine encephalomyelitis virus (TMEV) infection. In addition, cytokine levels produced after TMEV infection are significant...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jin, Young-Hee, Kaneyama, Tomoki, Kang, Min Hyung, Kang, Hyun Seok, Koh, Chang-Sung, Kim, Byung S
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293102/
https://ncbi.nlm.nih.gov/pubmed/22189096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-178
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