Deficiency of the lipid synthesis enzyme, DGAT1, extends longevity in mice

Calorie restriction results in leanness, which is linked to metabolic conditions that favor longevity. We show here that deficiency of the triglyceride synthesis enzyme acyl CoA:diacylglycerol acyltransferase 1 (DGAT1), which promotes leanness, also extends longevity without limiting food intake. Fe...

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Hlavní autoři: Streeper, Ryan S., Grueter, Carrie A., Salomonis, Nathan, Cases, Sylvaine, Levin, Malin C., Koliwad, Suneil K., Zhou, Ping, Hirschey, Matthew D., Verdin, Eric, Farese, Robert V.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2012
Témata:
Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3292902/
https://ncbi.nlm.nih.gov/pubmed/22291164
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