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Chemical genetic-mediated spatial regulation of protein expression in neurons reveals an axonal function for Wld(S)
The degeneration of axons is the underlying pathological process of several neurological disorders. The Wallerian degeneration (Wld(S)) slow protein, which is primarily nuclear, markedly inhibits axonal degeneration. Contradictory models have been proposed to explain its mechanism, including a role...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3292772/ https://ncbi.nlm.nih.gov/pubmed/22365601 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2012.01.012 |
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