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Reprogramming axonal behavior by axon-specific viral transduction

The treatment of axonal disorders, such as diseases associated with axonal injury and degeneration, is limited by the inability to directly target therapeutic protein expression to injured axons. Current gene therapy approaches rely on infection and transcription of viral genes in the cell body. Her...

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Autors principals: Walker, Breset A., Hengst, Ulrich, Kim, Hyung Joon, Jeon, Noo Li, Schmidt, Eric F., Heintz, Nathaniel, Milner, Teresa A., Jaffrey, Samie R.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426632/
https://ncbi.nlm.nih.gov/pubmed/22278412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2011.217
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