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AP-2β REGULATES AMYLOID BETA-PROTEIN STIMULATION OF APOLIPOPROTEIN E TRANSCRIPTION IN ASTROCYTES
Two key players involved in Alzheimer’s disease (AD) are amyloid beta protein (Aβ) and apolipoprotein E (apoE). Aβ increases apoE protein levels in astrocytes which is associated with cholesterol trafficking, neuroinflammatory responses and Aβ clearance. The mechanism for the increase in apoE protei...
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| Główni autorzy: | , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2012
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3292686/ https://ncbi.nlm.nih.gov/pubmed/22325097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2012.01.017 |
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