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Simvastatin Stimulates Production of the Antiapoptotic Protein Bcl-2 via Endothelin-1 and NFATc3 in SH-SY5Y Cells

The use of statins for the prevention or treatment of different neurodegenerative diseases has generated considerable interest albeit with some controversy. Mechanisms of statin-induced neuroprotection are not well understood. Recently, we reported that simvastatin stimulated neuronal gene expressio...

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Hlavní autoři: Butterick, Tammy A., Igbavboa, Urule, Eckert, Gunter P., Sun, Grace Y., Weisman, Gary A., Müller, Walter E., Wood, W. Gibson
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075856/
https://ncbi.nlm.nih.gov/pubmed/20369390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-010-8122-8
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