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The interaction of beta-amyloid protein with cellular membranes stimulates its own production
Gradual changes in steady-state levels of beta amyloid peptides (Aβ) in brain are considered an initial step in the amyloid cascade hypothesis of Alzheimer's disease. Aβ is a product of the secretase cleavage of amyloid precursor protein (APP). There is evidence that the membrane lipid environm...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2674130/ https://ncbi.nlm.nih.gov/pubmed/19366591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2009.01.012 |
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