Cyclin-dependent kinases regulate epigenetic gene silencing through phosphorylation of EZH2

The Polycomb group (PcG) protein, enhancer of zeste homologue 2 (EZH2), has an essential role in promoting histone H3 lysine 27 trimethylation (H3K27me3) and epigenetic gene silencing(1–4). This function of EZH2 is important for cell proliferation and inhibition of cell differentiation, and is impli...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chen, Shuai, Bohrer, Laura R., Rai, Aswathy N., Pan, Yunqian, Gan, Lu, Zhou, Xianzheng, Bagchi, Anindya, Simon, Jeffrey A., Huang, Haojie
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3292434/
https://ncbi.nlm.nih.gov/pubmed/20935635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2116
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