Mouse miRNA-709 directly regulates miRNA-15a/16-1 biogenesis at the posttranscriptional level in the nucleus: evidence for a microRNA hierarchy system

MicroRNAs (miRNAs) are endogenous noncoding RNAs (∼22 nt) that regulate target gene expression at the post-transcriptional level in the cytoplasm. Recent discoveries of the presence of miRNAs and miRNA function-required argonaute family proteins in the cell nucleus have prompted us to hypothesize th...

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Bibliographic Details
Main Authors: Tang, Rui, Li, Limin, Zhu, Dihan, Hou, Dongxia, Cao, Ting, Gu, Hongwei, Zhang, Jing, Chen, Junyuan, Zhang, Chen-Yu, Zen, Ke
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2012
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3292299/
https://ncbi.nlm.nih.gov/pubmed/21862971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2011.137
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