The landscape of miRNA editing in animals and its impact on miRNA biogenesis and targeting

Adenosine-to-inosine (A-to-I) RNA editing regulates miRNA biogenesis and function. To date, fewer than 160 miRNA editing sites have been identified. Here, we present a quantitative atlas of miRNA A-to-I editing through the profiling of 201 pri-miRNA samples and 4694 mature miRNA samples in human, mo...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Li, Lishi, Song, Yulong, Shi, Xinrui, Liu, Jianheng, Xiong, Shaolei, Chen, Wanying, Fu, Qiang, Huang, Zichao, Gu, Nannan, Zhang, Rui
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5749178/
https://ncbi.nlm.nih.gov/pubmed/29233923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.224386.117
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