Reduced Mitochondria Cytochrome Oxidase Activity in Adult Children of Mothers with Alzheimer's Disease

Biomarker studies demonstrate inheritance of glucose hypometabolism and increased amyloid-β deposition in adult offspring of mothers, but not fathers, affected by late-onset Alzheimer's disease (LOAD). The underlying genetic mechanisms are unknown. We investigated whether cognitively normal (NL...

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Hauptverfasser: Mosconi, Lisa, de Leon, Mony, Murray, John, Lezi, E, Lu, Jianghua, Javier, Elizabeth, McHugh, Pauline, Swerdlow, Russell H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3291954/
https://ncbi.nlm.nih.gov/pubmed/21841246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2011-110866
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